Okoye then found herself in conflict with her own husband, W’Kabi, after Klaue’s escape caused friction between him and T’Challa, a tension that was only exacerbated with Killmonger’s arrival in Wakanda. When Killmonger arrived with the dead Klaue and revealed he was the king’s long lost cousin, he swayed W’Kabi and filled his head with ideas of Wakanda ruling the world. Once Killmonger challenged, and seemingly killed, T’Challa in ritual combat and became the new king, Okoye had no choice but to obey him, as her duty was to whoever rightfully sat on the throne.
Once T’Challa revealed himself to be alive however, Okoye was relieved to recognize that since T’Challa had never submitted, the royal challenge wasn’t complete—Killmonger was not the true King, even as he refused to give up his rule. With Killmonger sending those loyal to him to attack T’Challa, Okoye and the Dora Milaje fought against Killmonger, her own husband, and his men when they wouldn’t relent. When W’Kabi, riding one of his tamed rhinoceros, charged M’Baku, who had decided to fight for T’Challa, Okoye stood in the way, causing the rhino to come to a halt and affectionately lick her face in recognition. Okoye made it clear she would kill W’Kabi for her country, leading him and his men to surrender, while Killmonger fell in battle with T’Challa.
Soon after, Okoye accompanied T’Challa to Vienna, as he stood before the United Nations and announced that Wakanda would now be opening itself up to the world.
Two years later, Steve Rogers AKA Captain America contacted T’Challa, asking for his aid to remove the Mind Stone from his ally Vision’s forehead, so that Vision wouldn’t have to sacrifice his life to destroy it before Thanos was able to obtain it for deadly purposes. Okoye accompanied T’Challa as they informed Rogers’ friend, Bucky Barnes, who’d been living among them in Wakanda, of the approaching fight, and also greeted Rogers and his allies when they arrived. Knowing that Thanos’ army was fast approaching, Okoye and T’Challa prepared all the tribes, and the Dora Milaje, for battle alongside the Avengers, while Shuri worked to remove the stone from Vision.
In a wild and ferocious fight, the fields outside of Wakanda were flooded by aliens in Thanos’ service, along with the Children of Thanos. When Proxima Midnight attempted to kill the Scarlet Witch, Okoye and Black Widow joined forces to fight Midnight, with a recovered Scarlet Witch stepping in to defeat her.